A prescription drug, or Norvasc, is an oral tablet that is used to treat high blood pressure (hypertension) and a condition that causes fluid to leak out of the body. It contains a compound called angiotensin II receptor antagonist, which is a type of antihypertensive agent that is in a class of drugs called angiotensin-converting enzyme (ACE) inhibitors. This drug is also in theamlodipine besylate tabletstablets.
Norvasc (amlodipine besylate) is available as the generic version. The drug was manufactured by Pfizer Inc., GlaxoSmithKline plc, Sandoz, and Zydus Pharm.
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Norvasc is the brand name for amlodipine besylate. Amlodipine besylate is a calcium channel blocker, which is a type of calcium channel blocker. This means it works to decrease the amount of calcium in the blood that is absorbed through the blood vessels.
The brand-name drug was approved by the FDA in 1997. Since then, Norvasc has been available in many different forms.
Norvasc (amlodipine besylate) is used to treat high blood pressure (hypertension) and angina (chest pain).
Amlodipine besylate is used to treat high blood pressure, or high blood pressure in the arteries of the heart and in the legs of the lungs. It works by relaxing the muscles that narrows the blood vessels and allowing blood to flow more easily.
Norvasc comes in two forms: an oral tablet and an oral suspension. The oral tablet is taken with water. The oral suspension is taken once a day. The liquid is taken with meals. The liquid may be flavored with other products that you can find at your local drug store, and it’s often sold in bottles.
There are no specific warnings for Norvasc. It is generally safe to take by mouth. However, some people may have a higher risk of side effects when taking Norvasc.
The drug may cause a condition known ashypertension. High blood pressure occurs when there is too much blood in the blood vessels, which can lead to. Lowering blood pressure can help lower blood pressure. Lowering blood pressure means that your blood pressure doesn’t become too low and your body becomes more relaxed.
If you have a kidney condition called nephrotic syndrome, this medication can cause a condition calledglaucoma—inflammation in the eye. This means that your blood pressure is too high and can lead to.
Norvasc is generally well-tolerated. It can cause side effects, including headache, fatigue, and stomach upset. Some people have a higher risk of getting these side effects if they take the drug with alcohol or grapefruit juice.
The risk of side effects increases if you have certain medical conditions, especially if you have diabetes or high blood pressure. You may have a higher risk of these side effects if you take Norvasc with certain medications.
A blood thinner called warfarin is used to prevent blood clots. It can cause a condition calledgastrointestinal bleeding—an abnormal blood flow or clotting reaction in the stomach, pancreas, or large intestine. This may happen in people at high risk for this reaction.
A kidney condition called nephrotic syndrome is also possible. People who have kidney disease have increased risk of kidney damage. You should be closely watched for these side effects if you are taking Norvasc.
The dosage of Norvasc is determined by a doctor. It’s usually taken with a meal. If you are on anamlodipine besylateoral tablet, a low-salt diet may be beneficial. It may also help you to decrease your blood pressure.
The medication should be taken only when needed.
Amlodipine
Norvasc 5mg
The recommended dose is 5mg once daily in the evening, 1mg every other day in the morning and at bedtime.
Avoid the consumption of alcohol during treatment with amlodipine. Patients with hypertension or edema (high blood pressure) should not take amlodipine. It is not known if amlodipine is contraindicated in patients with a history of coronary heart disease. Patients with anuria, which may be normal, who have a history of stroke or MI should not take amlodipine. Amlodipine should not be used in patients with kidney problems, particularly in patients on dialysis. Amlodipine may cause dizziness or drowsiness in patients with these conditions. Patients with a history of coronary heart disease, such as heart failure, should not take amlodipine. Patients with a history of coronary heart disease, such as heart failure, who have been taking amlodipine for at least 3 months, should not take amlodipine. Patients with a history of arrhythmia (arrhythmia is inherited in some people) should not take amlodipine. Amlodipine is contraindicated in patients with a history of heart failure, particularly in patients on high blood pressure.
May include headache, nausea, indigestion, diarrhea, constipation, dry mouth, dizziness, drowsiness, increased thirst, weight gain, irregular heartbeat, palpitations, and hypotension. In the elderly, a decrease in blood pressure and a reduction in blood pressure may occur. Increased thirst and increased urination may also occur. Patients who are allergic to amlodipine may be allergic to amlodipine. Amlodipine may decrease the effect of metoprolol on blood pressure. Amlodipine should not be used with other antihypertensive agents. Patients with known hypersensitivity to any of the ingredients of amlodipine should not use it. Patients with a history of heart attack or stroke should not take amlodipine. It is not known if amlodipine is contraindicated in patients with a history of heart failure. It is not known if amlodipine is contraindicated in patients with a history of angina (chest pain). Patients with liver or kidney problems should not take amlodipine. Patients with a history of hypersensitivity to any of the ingredients of amlodipine should not use it. Amlodipine is not indicated in patients with a history of hypertension or edema (high blood pressure).
Consult your doctor before taking amlodipine. Amlodipine is excreted in human breast milk. Amlodipine should not be taken during pregnancy.
May interact with:
Inhibitors of angiotensin converting enzyme (ACE) inhibitors: Amlodipine may reduce the blood pressure lowering effect of angiotensin II receptor blockers. Amlodipine may reduce the blood pressure lowering effect of angiotensin-converting enzyme (ACE) inhibitors. Amlodipine may decrease the blood pressure lowering effect of angiotensin II receptor blockers.
May include:
Gastrointestinal symptoms: Diarrhea, constipation, nausea, vomiting, diarrhea, or vomiting, dizziness, lightheadedness, dizziness, lightheadedness, and tinnitus, and headache.
Norvasc (amlodipine) is a prescription medication used to treat high blood pressure and angina. It works by relaxing the blood vessels and increasing blood flow to the heart. This helps to lower the workload on the heart and reduces the risk of heart attack or stroke. It belongs to a class of drugs known as calcium channel blockers.
Norvasc is available as a tablet. It is available in the dosage strengths of 50 mg and 100 mg. The strength of the tablet depends on the condition being treated. Your doctor will determine the dosage and frequency of use based on your medical condition.
Available strengths: The usual recommended starting dose for adults is 50 mg once daily. The maximum recommended dose is 100 mg per day. The dose can be increased to a maximum of 200 mg/day if prescribed by your doctor. The maximum recommended daily dose is 100 mg.
Do not take other types of medications for hypertension or high blood pressure:
If your doctor has prescribed Norvasc, you can take it either with or without food. If you eat a high-fat meal or use a heavy meal, do not take it, even if you feel well. This can cause side effects such as nausea, constipation, dry mouth, drowsiness, dizziness, and increased heart rate. Also, avoid alcoholic beverages.
The maximum recommended dose for treating high blood pressure is 100 mg, taken as needed, every 4 to 6 hours. Maximum recommended daily dose is 100 mg.
The dose of Norvasc for treating high blood pressure is usually 50 mg once daily, usually for 5 to 10 days.
Do not take an anti-hypertensive medicine in combination with Norvasc:
You should not take Norvasc if you are allergic to any of the ingredients in Norvasc tablets:
Norvasc is used to treat high blood pressure and heart conditions such as angina, and high blood pressure. It is also used to treat high cholesterol or high blood pressure. Norvasc works by relaxing the blood vessels in your heart and improving blood flow to your heart. The medication belongs to a class of drugs called calcium channel blockers. It blocks calcium in your heart's nerve cells, increasing the heart's response to exercise.
The world's top drugmaker has agreed to buy Pfizer Inc. for $1.6 billion, a price tag that analysts say is unlikely to cause the drug company to lose its patent protection.
The deal, announced yesterday by the pharmaceutical giant Pfizer, would see Pfizer pay out-of-court royalties on its biggest selling drug, Norvasc.
Pfizer will pay $1.6 billion to settle generic drug litigation that resulted in a patent loss, said Dr. Paul Dirsch, the chief executive of Pfizer, which is the largest pharmaceutical company in the world.
The deals are the latest attempt by the pharmaceutical industry to cut down on drug costs.
Norvasc, which blocks the calcium channel blocker calcium channel blockers, treats hypertension and angina, and was the company's first drug to win FDA approval to treat this indication.
Dr. Daniel Zook, Pfizer's chief financial officer, said the deal is the latest step in Pfizer's strategy toward cutting costs.
"The next step is to reduce the patent loss on Norvasc," said Zook, adding that Pfizer will pay out-of-court royalties for the full price of the drug.
The deal is subject to the FDA's approval and Pfizer's royalties will be used for marketing costs.
The announcement comes a day after Pfizer announced a price increase on Norvasc for a three-month supply, a charge that the company has not yet been told about.
Pfizer said the price increase will cost the company $1.6 billion to offset the $4.5 billion in revenue the drug generated in the first nine months of 2012.
The deal also comes after a $2.3 billion settlement with two pharmaceutical firms, the U. S. Food and Drug Administration, that led to a 10 percent royalty rate to be paid by Pfizer in the first quarter of 2013.
The drugmaker has been fighting back with the Justice Department over its patent challenge allegations, and Pfizer has been trying to persuade a federal judge to take a stronger enforcement measure against its drugmakers.
The settlement, announced yesterday by the pharmaceutical giant Pfizer, will provide Pfizer with a new incentive to reduce its spending on research and development, including a $100 million royalty payment to the company for all research and development costs.
Pfizer's lawsuit claims that the drug maker had been paid $2 billion for marketing the drug and the $4.5 billion in royalties it pays to the drug companies.
The settlement, announced yesterday by the pharmaceutical giant Pfizer, will give Pfizer the same incentive as other drugmakers, which were not allowed to produce the drug.
Pfizer had argued that the royalty payments would have been paid by Pfizer because it had already paid $2.3 billion to be the royalty payment for Norvasc.
The royalty payments would have been paid by Pfizer because the company was able to pay off its patent claims, Pfizer said in the settlement.
Pfizer is trying to get the drugmaker's patent to expire in 2014.
Pfizer shares closed at $30.28 on the New York Stock Exchange.
Image: Pfizer/ZENJIANPfizer, which has an estimated market capitalization of $1.6 billion, said it has reached an agreement with ZENJIAN to buy the drug maker's rights in Norvasc and sell the drug in the United States.
The deal, announced yesterday by the pharmaceutical giant Pfizer, would pay out-of-court royalties for the full price of Norvasc, the company said in a statement.
The company said it is in a "critical" phase of clinical trials for the drug.
Pfizer said that Norvasc was the first drug to win FDA approval to treat angina and that its patent protection was due to expire in 2015.
Pfizer shares closed at $18.40 on the New York Stock Exchange.
Stade de France Pharmacy